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They are indicated together with diet and physical activity in adults who have obesity (BMI of 30 kg/m2 or more) or overweight (BMI between 27 and 30 kg/m2) and have weight related health problems such as diabetes, abnormally high levels of fat in the blood, high blood pressure or obstructive sleep apnoea (frequent interruption of breathing during sleep)

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This concentration often comes paired with niacinamide (vitamin B3) at 2mg/mL as an added ingredient

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As a result, there is a growing argument to be made that providing coverage under group health plans to address obesity may be medically necessary and appropriate