MD simulations on the exendin-P5-bound complex revealed a similar C-terminal interaction pattern to exendin-4 for this peptide, with more persistent interactions with the ECD and TM1/stalk than GLP-1 (Fig
Diabetol Metab Syndr 16 , 293 (2024)
More recent work improving topical copper-peptide delivery demonstrated hair regrowth and Wnt/-catenin activation in mice a preclinical model, not people (Liu et al., 2023, DOI)
For healthy athletes, however, evidence for broad improvements in body composition or aerobic performance is mixed
This is a distinct entity from acidosis that results from paracetamol toxicity, which is due to liver derangement and lactic acidosis
it would spike and then I would take the insulin and it would come down