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The major putative benzoyl metabolites were then found to function as redox cyclers: (i) in their oxidized form, the benzoyl metabolites are reduced by NADPH in glutathione reductase-catalyzed reactions within the cytosols of infected red blood cells

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The Pharmacy Compounding Advisory Committee reviews scientific evidence, safety information and clinical need before making recommendations to the FDA regarding whether a substance should be included on that list