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GLP-1 receptor agonists (GLP-1 RAs) mimic a naturally occurring hormone in your body called glucagon-like peptide-1

GLP-1 receptor agonists have known GI side effects (nausea, vomiting, constipation, diarrhea) that are dose-dependent and generally manageable but affect adherence

Take-home perspective The central challenge in obesity management is no longer achieving weight loss, but maintaining it without sacrificing functional lean tissue

About the Experts Susie Reiner, Ph.D., is an exercise physiologist and founder of TheoryEx Performance, a scientific consulting agency

For example, a study of 643,687 levothyroxine users found that over-replacement was associated with higher AF risk (OR: 1.31, 95% CI: 1.241.38), while another study showed increased stroke risk (OR: 1.33, 95% CI: 1.241.43) [19, 36]

We also finalized revisions to 180.70(a)(2) to add activities that CMS may use to monitor and assess for compliance