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GLP-1 receptor agonists work through several mechanisms: they enhance insulin secretion when blood glucose levels are elevated, suppress glucagon release (which reduces glucose production by the liver), slow gastric emptying, and promote satiety through effects on appetite centres in the brain
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From a therapeutic perspective, GLP-1 receptor agonists drugs that mimic the endogenous hormone GLP-1 are used to treat type 2 diabetes and obesity by improving insulin secretion, lowering blood sugar, and supporting weight reduction
