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In a subgroup of 98 participants with nonalcoholic fatty liver disease in the trial, 90% of participants in the highest dose of retaglutide group had normalized liver fat content

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[1] [2] This low introductory dose is intentional it allows the body to gradually adapt to the drug's pharmacological effects before the dose is escalated

Semaglutide is well-tolerated in clinical practice when dosed appropriately