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We propose that the dosage and duration of GSH administration in clinical treatment be carefully evaluated and standardized to prevent overuse and mitigate the risk of chemotherapy resistance

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THERAPEUTIC INTERVENTIONS CLINICAL EXAMPLES AND THERAPEUTIC FORMS: N-acetylcysteine (NAC) Improving cellular glutathione status remains a clinical challenge, though interventions which enhance glutathione synthesis have for the most part been successful, most notably N-acetylcysteine (NAC)

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