This matters because muscle supports strength, balance, glucose handling, metabolism, mobility, and long-term weight maintenance
The mechanism of action includes several key effects: they stimulate insulin secretion from pancreatic beta cells in a glucose-dependent manner, suppress glucagon release (which reduces hepatic glucose production), slow gastric emptying, and act on appetite centres in the brain to promote satiety and reduce food intake
You can increase this to 5 mg after four weeks, continuing to titrate up to a maximum of 15 mg, allowing a potentially more significant effect on blood sugar and weight loss
For postpartum women with insulin resistance, PCOS, or gestational diabetes that persists after delivery, metformin may serve double duty by managing blood sugar and supporting weight loss
PlexusDx also offers the Microdose GLP-1 Protocol at $129 per month for patients requiring gentler initiation, and all treatments are HSA/FSA eligible to lower your out-of-pocket cost
Breastfeeding also increases your need for energy and key nutrients, so overly restrictive eating plans can easily lead to nutrient deficiencies and make it harder to maintain milk supply