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The experiments were conducted on Albino Wistar rats and Hartley guinea pigs

A crucial role of lactate accumulation in cancer cells has been demonstrated regarding its ability to induce expression of anti-inflammatory and proangiogenic genes, together with the modification of histones through a process called lactylation, where a lactyl-CoA is added to lysine residues present in the tails of histones [33]

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While the kidneys play a pivotal role in filtering waste and maintaining fluid balance, they are also highly dependent on a delicate balance of nutrients and antioxidants, including glutathione

ALC was incorporated into D12108 feed containing 1.25% cholesterol to produce an HCD with an ALC concentration of 300 mg/kg