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The majority of the reported events occurred in patients who had experienced gastrointestinal reactions leading to dehydration such as nausea, vomiting, or diarrhea

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Orexinergic Neurons: Targeted modulation or suppression of orexin overexpression helps decrease wakefulness and prolong REM/NREM balance

H., Dhurandhar, N

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Proprotein convertase subtilisin/kexin type 1 (PCSK1), initiates cleavage of POMC into melanocortin family peptides, including - and - melanocyte stimulating hormones (MSH, MSH) 30