week 3 semaglutide side effects Effects: What Patients Should Know in 2025 FDA alerts health care providers,

Cell Metabolism , 17 , 6172

Higher diabetes risk

This distinguishes it from better-known compounds such as semaglutide (Ozempic/Wegovy), which targets only the GLP-1 receptor, and from tirzepatide (Mounjaro/Zepbound), which is a dual GLP-1/GIP agonist

Vitamin D deficiency was strongly associated with a higher risk of alopecia areata, with a pooled odds ratio of 2.48, meaning those with low vitamin D levels were over twice as likely to develop alopecia areata

If you want the mechanism-level breakdown, our guide on what retatrutide is and how it works explains why the triple-agonist design has become such a big deal

Altered differentiation in rat and rabbit limb bud micromass cultures by glutathione modulating agents