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2017 Jan 15;440:106-115 16.1 Duntas LH

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The presence of Nrf2 and its inhibitor Keap1 in plasma is associated with damaged vascular endothelial cell-, macrophage-and other cell-associated leakage secondary to the loss of cell membrane integrity due to lipid peroxidation following chronic inflammation and oxidative stress (Kasprzak et al., 2020), and Nrf2 and Keap1 in circulation are markers of severe inflammation and oxidative stress (Tu et al., 2019)

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Modulation of human serum glutathione S-transferase A1/2 concentration by cruciferous vegetables in a controlled feeding study is influenced by GSTM1 and GSTT1 genotypes

In order to substantiate the therapeutic potential of JMF4073 for TKI-resistant T315I-Bcr-Abl cells, we investigated the mechanism responsible for the differential response to JMF4073