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Oxidative Stress Biomarkers and When Glutathione May Be Clinically Relevant Glutathione's role as an intracellular antioxidant is biochemically sound, but supplementation doesn't directly measure whether your oxidative stress burden actually warrants intervention

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The discovery of sodium-channel block as the major mechanism underlying antiarrhythmic effects of quinidine led to the development of class I antiarrhythmic agents such as flecainide and propafenone