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But by comparison, semaglutide led to some users losing an average of 12 percent of their weight in around six months

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Discussion Our results demonstrate that GLP-1 receptor agonists provide better cardiovascular protection than SGLT2 inhibitors in patients with HFpEF and DM, significantly reducing the risk of cardiovascular events, progression to SHF, and stroke

doi:10.1016/j.neuropharm.2017.11.048 60