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Serum limitation-induced organ culture model of keloids and apoptotic induction of FOXO4-DRI in situ The keloid tissues were cut into 4-mm diameter cylinders using a corneal trephine for organ culture and cultured in a DMEM containing 2% FBS for 10 days to construct the serum limitation-induced senescent organ culture model of keloid tissues

No long-term safety data

Hair Growth and Restoration Protocol Dose: 2 mg per day (injectable) or 1.5 to 2.5% topical applied to scalp Route: Subcutaneous or topical Frequency: Daily injection (5 days on, 2 off) or twice daily topical Cycle: 16 to 24 weeks minimum Expected results: Reduced shedding at 4 to 8 weeks

(2013d)

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GGT1 knockdown cell lines had minimal GGT1 mRNA (Extended Data Fig