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Some notice brief, mild GI effects tied to the methionine and choline in the formula

It failed to gain approval for obesity treatment following Phase II clinical trials in the mid-2000s, and no regulatory body has since approved it for any human indication

After absorption, B12 is bound to transport proteins, 7580% to haptocorrin, which transports B12 in the blood, and 2025% to transcobalamin, which delivers B12 to the tissues, also referred to as active B12 or holo-transcobalamin

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Patients often report that they did not realize how poor they felt until B12 began to help their bodies