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Several large RCTs have shown that liraglutide and semaglutide are significantly more effective than controls in reducing liver fat content or resolving NASH [20-22]

Meanwhile, NNMTi preserves lean body mass: it reduces fat accumulation without causing muscle loss, which is crucial for maintaining basal metabolism and preventing weight regain after dieting.These in vivo findings fully validate the efficacy and safety of NNMTi in obesity intervention, laying a solid foundation for its subsequent clinical research and drug development

The medication also acts on areas of the brain involved in appetite regulation, further reducing food intake

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8-9 Studies supporting acupuncture for NAION typically employ acupoint combinations targeting ocular blood flow and nerve regeneration