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It is possible that studies with negative or non-significant results were less likely to be published, which could lead to an overestimation of treatment effects

Compared with the placebo group, treatment with the GLP-1 analog liraglutide reduced the rates of non-fatal myocardial infarction, non-fatal stroke and hospitalization for heart failure (52)

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Safe GLP-1 Use: Monitoring and Prevention Strategies Starting GLP-1 therapy at the lowest effective dose allows your digestive system to adapt gradually while minimizing gastrointestinal disruption