SOD isozymes are present in the cytosol and mitochondria in plants, and there is also an iron SOD found in chloroplasts
Napoli PE, Braghiroli M, Iovino C, Demarinis G, Fossarello M
However, neuroinflammation has also been evidenced by 11 C-(R)-PK11195 PET imaging to be associated with ME/CFS (132), and shown to contribute to the pathophysiology of this disease (133, 134)
Glutathione, a major intracellular non-protein thiol, protects against free radical damage by providing reducing equivalents for several key antioxidant enzymes
secondly, the study sample was relatively small
All in all, although the results of a recent meta-analysis have shown that CoQ10 is an effective and safe supplement for reducing fatigue symptoms, more extensive and controlled studies are essential to further substantiate the advantages of Ubiquinol-10 supplementation [137]