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3 COF-based reactor and command center for cancer-immunity cycle As cancer immunotherapy research enters a more complex phase, single-mode interventions are increasingly insufficient to overcome the formidable barriers posed by tumor heterogeneity and the immunosuppressive microenvironment (161, 162)

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[DOI] [PubMed] [Google Scholar] 216.Cheng GC, Schulze PC, Lee RT, Sylvan J, Zetter BR, Huang H