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Ocular side effects There is a reported increased risk of diabetic retinopathy with GLP-1 agonists, specifically semaglutide (Ozempic, Wegovy) as demonstrated by the SUSTAIN-6 trial (HR 1.76

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2) but also modulating precursor amino acids supplies could elevate EGT production

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Nevertheless, these models have helped to identify oxidative stress via photooxidation, and photosensitisation as major factors involved in UV cataract development