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Liposomes as advanced delivery systems for nutraceuticals
Is it the abnormal intestinal microbiota that causes increased intestinal permeability and translocation of bacteria as well as their products and the development of disease, or is it the disease that causes a systemic inflammatory response resulting in disruption of the intestinal barrier, subsequent translocation of bacteria and further damage to the organ
Epidemiological studies showed that genes contribute to the vulnerability of multiple CNS disorders, such as major depressive disorders (MDD), schizophrenia and substance use disorders with heritability respectively of 3142%, 6480%, and 2379% [10,11,12,13]
(11) This has led to the hypothesis that exogenous FOXO protein, such as FOXO4-DRI peptide, may help regulate optimal levels of FOXO proteins, thereby preventing or alleviating the progression of any NDDs associated with this mechanism
