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And yet any consumer seeing the kind of marketing and claims on packages would likely infer that many of them do have those effects. Part of the problem, Austin said, is that many individuals find the high price of most weight-loss prescription medications prohibitive, dislike the idea of self-injecting medication (how both Wegovy and Zepbound are administered), or struggle with unpleasant side effectsfurther fueling interest in unregulated alternatives

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Antihyperalgesic effects of (R,E)-N-(2-hydroxy-2,3-dihydro-1H-inden-4-yl)-3-(2-(piperidin-1-yl)-4-(trifluoromethyl)phenyl)-acrylamide (AMG8562), a novel transient receptor potential vanilloid type 1 modulator that does not cause hyperthermia in rats