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This transporter is responsible for absorption of folate in the intestine [112, 113]

Protocols vary: Initial loading : 1,000 mcg every other day for 12 weeks Taper : Weekly injections for 46 weeks Maintenance : Monthly injections Injections are critical for pernicious anemia or severe malabsorptive states

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Elevated serum B12 levels (hypercobalaminaemia) detected on blood tests may indicate underlying conditions such as liver disease, kidney dysfunction, or myeloproliferative disorders rather than representing a direct cause of symptoms

Methylcobalamin is a naturally occurring form, often favored by those looking for a 'body-ready' version