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Selectivity profiling indicates activity on ERRs with minimal cross-activation of classical ER/ER or unrelated nuclear receptors at concentrations relevant to the ERR program

Without it, your metabolism slows slightly, your hunger increases significantly, and your body becomes remarkably efficient at storing calories as fat

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10.1016/j.arr.2020.101191 Ageing Res

GSTs catalyze the conjugation of tripeptide glutathione (GSH) with endogenous electrophilic compounds (secondary metabolites, hydroperoxides) and xenobiotics, such as herbicides, leading to their cellular detoxification