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Once the cells became confluent, the medium in the plates was switched to adipose differentiation medium 1 (Solution A: 0.5 mmol/L isobutyl-3-methylxanthine, 1.7 nmol/mL insulin, 1 mol/L CORT, 10% FBS, high-glucose DMEM

Among the diverse array of antidiabetic agents, the class of GLP-1 receptor agonists has garnered substantial attention not only for their glycemic control properties but also for their potential cardiovascular benefits (8)

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In the future, the researchers hope to clarify the long-term impact of GLP-1 medications, the HFpEF subpopulations that may derive the most benefit from them, and whether the drugs are also effective in reducing other cardiovascular risks

Ottawa, ON: Canadian Pharmacists Association