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Therefore, a holistic, de-medicalized, and systemic approach to health could move models of preventive and therapeutic strategies from simple associations rooted in empirical reductionism toward the appreciation of network-based models (29, 45, 179182)

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Glutamate-cysteine ligase catalytic and modulator subunits as well as GSH synthetase are the three NRF2 targets involved in the GSH synthesis (242)

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