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Participants in trials lost an average of 20.9% of their body weight on the highest dose

However, because it drastically reduces your appetite, you may experience a drop in micronutrient intake if your diet is not carefully managed

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If users experience symptoms such as difficulty swallowing or swelling in the neck, immediate medical attention is advised

The effect of kidney disease, in particular, is quite pronounced: pre-dialysis patients may have twice the level of TMAO, and hemodialysis patients may have 10 times the level of TMAO as otherwise healthy patients

doi: 10.1002/mnfr.200800169