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The evidence base for the proposed use and its limitations: primarily preclinical, or limited human studies not conducted under Western regulatory standards

Search Strategy We searched PubMed, Embase and the Cochrane Central Register of Controlled Trials (CENTRAL) databases from their inception up until 31st July 2023 for clinical trials that compared once weekly tirzepatide (5, 10 and 15 mg) with placebo or GLP-1 RAs in adults with overweight or obesity

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Matthew Posewitz Biochemist PhD, Dartmouth Algal Biotechnology Read full bio FAQ GLP-1, or glucagon-like peptide-1, is a hormone found in your gut that helps control your blood sugar and appetite

Specific peptides prescribed for specific indications and dispensed by a licensed compounding pharmacy are legal for that named patient

Even a single unrecorded fluctuation can result in audit failures and lost accreditation