Concentration: How many milligrams per milliliter (for example, 10 mg/ml or 20 mg/ml)
Thus, basal ganglia activity may influence the cerebellum via projections of the STN to pontine nuclei which then project to the cerebellum [53]
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Dose escalation phase (titration) Tirzepatide titration (dose escalation) typically follows this schedule: Month 2: 4-6 mg once weekly Month 3: 6-8 mg once weekly Month 4: If tolerated, increase to 8-10 mg once weekly Month 5: If the dosage needs to be escalated further, increase to 10-12 mg once weekly Month 6 and onward: If the dosage needs to be escalated further, increase to 12-14 mg once weekly The maximum dosage is typically 14 mg once weekly if further glycemic control or weight loss is required
