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Taken together, evidence from neuroscience, human research, and clinical practice suggests meaningful overlap between obesity and addiction-related mechanisms. Lorenzo Leggio, MD, PhD, clinical director, National Institute on Drug Abuse, Bethesda, Md

For some patients, that is sufficient

The starting dose feels like wasted time

GLP-1 medications may be preferred over other weight loss drugs due to their non-stimulant nature, reducing the risk of side effects related to stimulant medications

Summary You Have Done the Research

It can be used as monotherapy when metformin is inappropriate, or in combination with other glucose-lowering medicinal products, including insulin, when these alone are inadequate