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Although the literature showing that GSH levels are lower in patients with tuberculosis dates back to the 1950s, it was not until the research of Venketaraman and colleagues that the effect of GSH on M

NADPH is an essential co-factor for both xenobiotic conjugation and antioxidant enzymes as well as a key element to switch cell metabolism toward the anabolic phase

The interacting proteins can then be eluted and analyzed, typically through SDS-PAGE followed by mass spectrometry or Western blotting, to identify and characterize the protein interactions

Beyond its direct antioxidant capabilities, glutathione plays a mandatory role in the Phase II detoxification of heavy metals and environmental pollutants

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