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Nakaya M, Xiao Y, Zhou X, Chang JH, Chang M, Cheng X et al (2014) Inflammatory T cell responses rely on amino acid transporter ASCT2 facilitation of glutamine uptake and mTORC1 kinase activation

Bacteroides dorei and Roseburia inulinivorans , the 2 identified positive microbial signatures at a species level, may cause immunomodulation ( Bacteroides dorei upregulated expression of tight junction genes in the colon and reduced microbial lipopolysaccharide production, thereby reducing gut permeability, and ameliorating endotoxemia ( Bacteroides dorei in patients with coronary artery diseases ( Roseburia inulinivorans had butyrate-producing and anti-inflammatory properties

Future direction and what to watch for stakeholders and industry peers

CagriSema is not FDA-approved as of the date above

FDA approved for moderate to severe OSA in people with obesity

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