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A volume of 0.5 mL of cyst suspension approximately equal to 0.4 g of wet tissue was injected by 16 ga needle intraperitoneally into SCID mice (Charles River)

Febuxostat is approved by the FDA to start at 40mg daily, and if the uric acid has not reached goal (less than 6.0mg/dL) after two weeks of treatment the dose can be increased to 80mg daily

Nguyen, Boosting the biogenesis and secretion of mesenchymal stem cell-derived exosomes

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otherwise, the challenges posed by an excessively growing aging population will become unmanageable (Gonzalez-Freire et al., 2020)