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Experiments have found that overexpression of the NF-B subunit and NF-B target genes in esophageal tissues of mice with GERD and down-regulation of the tight junction complexes, claudin1 and claudin4, resulted in esophageal barrier dysfunction in the mice

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This article is based on research published in Alternative Therapies in Health and Medicine (2021) by Edwin Lee and Blake Padgett

Funding This work was financially supported by the Postgraduate Scientific Research Fund Project of Zhejiang Chinese Medical University (No

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Lab markers (fasting glucose, insulin, lipid panel) typically show meaningful improvement