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If more than two weeks pass, some doctors might suggest restarting treatment at a smaller dose to ease stomach issues

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Three monoclonal antibody drug candidates are also being developed, two of which (apitegromab and trevogrumab) are intended for use alongside marketed weight-loss drugs to preserve lean muscle mass during medicalised weight-loss

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Materials and methods : Animals were provided with 1.3 bis( p -Hydroxyphenyl)urea at 12.5, 25, 50, 100, and 200 mg/kg BW