Insulin Resistance, Brain Atrophy, and Cognitive Performance in Late Middle-Aged Adults
Metformin, one of the most widely used diabetes drugs, has also been studied for its potential to protect the brain and reduce dementia risk
It helped control these patients glycemic numbers AND helped them lose weight
391 GLP-1 and GLP-1 analogs exert their effects on food intake and body weight through a myriad of neural substrates, encompassing several hypothalamic nuclei (including the arcuate nucleus of the hypothalamus, periventricular hypothalamus, and lateral hypothalamic area), hindbrain nuclei (such as the parabrachial nucleus and medial nucleus tractus solitarius), the ventral subregion of the hippocampus (vHP), and nuclei embedded within the mesolimbic reward circuitry (including the ventral tegmental area, VTA, and nucleus accumbens, NAc)
If you cannot figure out if a supplement has been third-party tested, this is a major red flag
If youre fatigued, ensure youre getting enough sleep and that youre eating throughout the day
