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IV NAC has a 1020% risk of anaphylactic reaction, and transfusion should not be halted for minor reactions of flushing.60,72 Other identified side-effects of NAC include nausea, vomiting, diarrhea or constipation, and rarely fever, headache, drowsiness or hypotension

However, evidence is mixed, and more research is needed to understand its potential benefits and risks

Comfort with Injections If you are uncomfortable with weekly injections or have a fear of needles, this may be a helpful alternative for you

Unsweetened herbal tea: Ginger or peppermint may feel gentler during nausea for some people

However, when the cell detects an apoptotic stimulus, such as DNA damage or metabolic stress, the intrinsic apoptotic pathway is triggered and mitochondrial cytochrome c is released into the cytosol ( c and then its translocation through permeabilized OMM

doi:10.1056/NEJMoa2304286 69