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Selenium is critical as it's required for glutathione peroxidase, an enzyme that uses glutathione to neutralize harmful peroxides

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361 However, p16 INK4a does not universally induce HSC senescence in all contexts, and its role in maintaining HSC homeostasis has not been reported in other studies

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This review summarizes the pharmacological mechanisms of selected botanical drugs in combating OS in ALD, offering a foundation for future studies on potential therapeutic agents for the treatment of alcoholic liver disease (Table 2)

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