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Rduction du lactate
Studies show that CrAT overexpression in primary human skeletal myocytes increases glucose uptake and attenuates lipid-induced suppression of glucose oxidation, demonstrating the importance of carnitine-dependent metabolic pathways in preserving insulin sensitivity and metabolic health
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doi: 10.3390/jcm12185921 34 GarveyWTBatterhamRLBhattaMBuscemiSChristensenLNFriasJPet al
However, their effects on MASH remain uncertain, as robust clinical trial evidence with histological liver endpoints is lacking (Mantovani et al., 2021[47], 2022[39])
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