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Mice were group-housed by gender at 20-24C, 45-65% humidity and exposed to a 12-hour light/12-hour dark period

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Overall, these observations demonstrate that LC and even R individuals present an altered metabolomic profile even ~12 months post the acute disease onset

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Typical Weekly Pattern During This Phase Weight loss: 0-0.5 pounds weekly average, with frequent plateau weeks Appetite: Remains suppressed compared to baseline but increased compared to weeks 8-28 Energy: Stable at levels established in weeks 25-36 Side effects: Essentially none