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Recent studies suggest that intestinal dysbiosis may trigger a series of biological responses, which include increased intestinal permeability, translocation of microbes or their metabolic products (i.e., lipopolysaccharides (LPS)), activation of immune responses, and cytokine release leading to gut inflammation and further worsening of the intestinal barrier permeability [41,50,90]

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Even for those who lose minimal weight on the drug, he's noticed a loss of elasticity

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