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They are about collagen that is disorganized, degraded, or remodeled in a way that reduces tensile strength

The proposed therapeutic mechanism involves the down-regulation of c-Jun-N-terminal kinase (JNK) by inducing Gadd45-beta activity, which ultimately disrupts a mechanism of mitochondrial damage

The increased GSH/GSSG ratio indicates enhanced antioxidant capacity and improved cellular resilience to oxidative insults

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