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419,420,421,422 Loss of astrocytes leads to an overall decrease in neuroprotection and affects neurotransmission

The depletion of systemic glutathione also plays a central, often overlooked role in the pathogenesis of mast cell activation syndrome (MCAS) and dysautonomia

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however, under ecological disturbance conditions, they can behave as pathobionts and shift towards opportunistic pathogenicity 128

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