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While both IGF-1 LR3 and IGF-1 DES activate the same receptor (IGF1R), their half-lives, delivery methods, and mechanisms of action lead to different safety profiles

Long-term follow-up studies are needed to assess durability of therapeutic effects and to identify any delayed adverse effects or complications that might not be apparent in shorter-term investigations

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Common signs include fatigue, brain fog, low mood, and tingling in hands or feet