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doi: 10.1016/s0002-9378(15)30003-x 13 HalmeJHammondMGHulkaJFRajSGTalbertLM

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Common causes of a rotator cuff tear include natural changes in the tendons that come with aging, repeated overhead movements, sudden injuries such as falls, and having a history of shoulder issues like arthritis

Factors such as age, sex, baseline fitness level, genetic polymorphisms, and even vitamin D status may modulate the degree to which these growth factors are upregulated

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A third key difference between these two peptides is that sermorelin has passed human clinical trials and received FDA approval but this was subsequently withdrawn in 2008 [3]