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This review is published in the PlexusDx Education Hub, our evidence-based library on GLP-1 therapy, weight management protocols, and the genetics behind metabolic results

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We titrate doses slowly to minimize discomfort

Post-fixation processing was performed in 1% osmium tetroxide for 2 h

290 In addition, p53 plays a critical role in regulating CVDs, including myocardial ischemia/reperfusion injury, heart failure, pressure overload- and diabetes-induced maladaptive remodeling and atherosclerosis

The TRIUMPH-4 population (obesity + knee osteoarthritis) may have elevated baseline susceptibility due to existing nerve compression from joint inflammation