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Also poorly understood is the potential relationship that may exist between hepatocyte swelling in response to amino acids, the obligatory KCC-dependent K + /Cl extrusion, the resulting reduction in [Cl ] i and glycogen synthesis via activation of the Cl -dependent enzyme glycogen synthase phosphatase (Meijer et al., 1992)

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Buckinx F, Aubertin-Leheudre M (2022) Sarcopenia in menopausal women: current perspectives

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In the future, the identification of specific genes or pathways could serve as direct targets, in conjunction with cysteine deprivation for cancer therapy