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doi:10.1159/000064531 4

Optimizing the substituent on the benzimidazole nitrogen proved a fruitful approach to improve potency without detrimentally impacting physiochemical properties, with smaller, more polar groups preferred

By integrating redox biology , adaptive materials design , and computational intelligence , next-generation HAGSH scaffolds are poised to evolve from passive wound dressings into autonomous biomaterial platforms capable of sensing, responding, and regenerating in synchrony with the bodys natural healing dynamics

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Macrophage-derived reactive oxygen species suppress mir-328 targeting Cd44 in cancer cells and promote redox adaptation