This reduces the risk of hypoglycaemia compared to some other diabetes medications, though this risk increases if used alongside insulin or sulfonylureas
We start low and adjust based on healing response. This is not just a dosing strategy
GLP-1 agonists are typically used continuously rather than cycled
More serious risks include pancreatitis, gallbladder disease, acute kidney injury from dehydration, and hypoglycemia (when used with insulin or sulfonylureas)
J Mol Cell Cardiol 46(1):4758 Pitkanen S, Merante F, McLeod DR, Applegarth D, Tong T, Robinson BH (1996) Familial cardiomyopathy with cataracts and lactic acidosis: a defect in complex I (NADH-dehydrogenase) of the mitochondria respiratory chain
Simultaneously, MMP activity (the enzymes that digest matrix) gets regulated alongside their inhibitors (TIMPs)